hinkley 20 hours ago

Oh I know we are trying to genomically test them for oncology research and potential treatment plans, but do they do paternity tests on them?

I was trying to remember which mammal in Australia gets tumors from fighting, and I found a reference to a mother getting melanoma from her daughter. It’s unclear to me whether the cancer transmission was rare or the identification is rare.

3
rflrob 19 hours ago

There’s very often a comparison to the somatic (i.e. non-cancer) genome of the same patient. It’s a great way to quality control that there wasn’t some sample mixup in the lab.

Transmission of cancer is rare in humans—if it were not, it would make someone’s career to find many cases of it. While we can’t say that all sheep are white, we’ve looked at enough of them to say that black sheep are not common. Furthermore, it’s very clear how the Tasmanian devil cancer is spread—it’s around the mouth while they are biting each others faces; it’s not as obvious how one would spread most human cancers.

hinkley 18 hours ago

Oh that makes sense. I forgot about differential analysis.

jjtheblunt 17 hours ago

Is HPV an example?

cogman10 17 hours ago

Not really. It's a virus that can cause cancer and not the cancer itself.

tdullien 2 hours ago

Tasmanian devils.

dekhn 19 hours ago

tasmanian devils [edit: I guess you already said that] https://en.wikipedia.org/wiki/Devil_facial_tumour_disease

hinkley 18 hours ago

Yup. Link is handy though. Someone will post it to the front page in 14 hours :)