Latency.
Twitch streamers seem to be fine with the 10-60 second latency Twitch adds, depending on how bad their network is performing. Requirements will differ per industry but I don't think latency is a killer necessarily.
Twitch does not add 10-60 seconds of latency. The average latency with default OBS settings is 3-6 seconds.
Source: I worked on the Twitch video system for 6 years.