There's a lot of risk in creativity when you're selling crap to the public at scale. Way better to just use what everyone else is using.
For most things cylindrical cells are the right answer. They don't puff up, they're available with protection circuits, they're cheap and highly available, you can get them in a variety of sizes and capacities, even in different chemistries.
Using a custom cell might make sense if you are making a) one megakajillion of a thing or b) you have extreme volume limits which mean you're probably using a pouch cell.
In HW engineering, Not Invented Here syndrome costs you big money. You have to have an actual business case for re-engineering something that already exists plus the capital.
95% with my stuff of the time COTS cylindrical is the answer, which means my shit comes in on budget.