There's a good deal of sci-fi on the topic. My favorite of them is Neal Stephenson's Fall; or, Dodge in Hell.
For me it's Greg Egan's Permutation City.
That one's on my to-read list...
Add Diaspora by Greg Egan to the simulated minds reading list (the story Wang's Carpets within it is one of my favorites).
Bump it up.
The Bobiverse series