It could be useful for content creators that value reusing their Python expertise over other factors. Also, many apps work better when every integrated component is written in the same language. Also, there’s a lot of code in Python for or supporting web programming. Finally, if people use AI auto-complete, many people say they’re more effective at common uses of Python vs other languages or situations.

I’ve found the performance issue to be serious in some situations. Fortunately, there’s a number of accelerators for Python code that boost its performance. They range from JIT’s (eg PyPy) to custom VM’s (eg Cinder) to writing fast paths in Cython to Python-to-C++ compilers (eg mycpp).

So, you get the productivity and familiarity of Python with performance boosting in many use cases. If it doesn’t work, then it’s better to write that component as an extension in a systems language.